A hemodynamic and histomorphometric analysis of the human right coronary artery by Anish Kirpalani

Cover of: A hemodynamic and histomorphometric analysis of the human right coronary artery | Anish Kirpalani

Published by National Library of Canada in Ottawa .

Written in English

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Edition Notes

Thesis (M.Sc.) -- University of Toronto, 1996.

Book details

SeriesCanadian theses = -- Thèses canadiennes
The Physical Object
FormatMicroform
Pagination1 microfiche : negative. --
ID Numbers
Open LibraryOL16986890M
ISBN 100612192601

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Background. Local hemodynamics plays an important role in atherogenesis and the progression of coronary atherosclerosis disease (CAD). The primary biological effect due to blood turbulence is the change in wall shear stress (WSS) on the endothelial cell membrane, while the local oscillatory nature of the blood flow affects the physiological changes in the coronary by: 9.

Hemodynamic Computation Using Multiphase Flow Dynamics in a Right Coronary Artery FIGURE 1. 3-D computational mesh for a realistic coronary artery generated using Cooper mesh generation algorithm and GAMBIT software.4,19 The geometry was reconstructed from the views of coronarography.

Point (1): inlet; point (2): the end of a straight. Download Citation | On Jan 1,Steven Robert Axon and others published Correlation of the hemodynamics and histology in the human right coronary artery | Find, read and cite all the research. A nonocclusive flushing technique was used for blood clearance by injection of contrast media.

The acquired data were stored in DICOM format and transferred to a workstation for further analysis. Coronary artery reconstruction. Coronary artery reconstruction was implemented using a well-established and validated methodology.

In x-ray Cited by: 8. Introduction. The leading causes of death and disability in the western world are disorders related to the vascular system ().Annually, coronary artery diseases (CAD) are responsible for million deaths and 58 million disability-adjusted life years lost worldwide ().Since in vivo measurements of the wall shear stress (WSS) and other hemodynamic parameters are difficult to perform in the.

Coronary arterial stenoses, particularly serial stenoses in a single branch, are responsible for complex hemodynamic properties of the coronary arterial trees, and the uncertain prognosis of invasive intervention.

Critical information of the blood flow redistribution in the stenotic arterial segments is required for the adequate treatment by: 8. Introduction. The distribution of wall shear A hemodynamic and histomorphometric analysis of the human right coronary artery book (WSS) in coronary arteries is a significant contributory factor for the onset of coronary ly, there have been some debates as to what degree of WSS or large WSS gradients is contributory to the onset of plaque formation and rupture at the same time.

Various studies have gone into explaining how regions are differentiated into Cited by: Morphometric and Hemodynamic Analysis of Atherosclerotic Progression in Human Carotid Artery Bifurcations Article in AJP Heart and Circulatory Physiology (5):ajpheart January.

The aim of this study was to develop a fully subject-specific model of the right coronary artery (RCA), including dynamic vessel motion, for computational analysis to assess the effects of cardiac-induced motion on hemodynamics and resulting wall shear stress (WSS). Vascular geometries were acquired in the right coronary artery (RCA) of a healthy volunteer using a navigator-gated Cited by:   Cardiac MRI: Short-axis perfusion scans of the heart at rest (Panel A) and under adenosine stress (Panel B): the arrows point out the area of inducible ischaemia; (Panels C and D) Coronary angiogram: RAO 30° and LAO 60° angiography, respectively of the left coronary system and of the small arrow point at the narrow segment of a transspetal branch suppling the Author: Andrea Denegri, Nooraldaem Yousif, Robert Manka, Hatem Alkadhi, Willibald Maier.

Introduction. Coronary artery disease (CAD) has become the most common cause of death in developing countries. In China, CAD was responsible for 17% of the mortality among the 50 most common causes of death, and this percentage has climbed to above 40% in [].The presence of a coronary arterial lesion is the major contributing factor to adverse clinical outcomes [].Cited by: 8.

Annually, coronary artery diseases (CAD) are responsible for million deaths and 58 million disability-adjusted life years lost worldwide (2). Since in vivo measurements of the wall shear stress (WSS) and other hemodynamic parameters are difficult to perform A hemodynamic and histomorphometric analysis of the human right coronary artery book the artery, computational fluid dynamics (CFD) technique has been used as an.

Hemodynamics analysis of the serial stenotic coronary arteries XinmLiu1†,mChangnongmPeng2†,mYufa mXia 3†,mZhifanmGao3,4,mPengchengmXu1,mXiaoqing mWang 2,mZhanchaomXian2,m Youbing mYin 5,mLiqunmJiao6,mDefeng mWang 7,mLinmShi7,mWenhua mHuang 1*,mXinmLiu3*mandmHeyemZhang3* Background As the cardiovascular disease(CVD)s become Cited by: 8.

Development of many conditions and disorders, such as atherosclerosis and stroke, are dependent upon hemodynamic forces. To accurately predict and prevent these conditions and disorders hemodynamic forces must be properly mapped.

Here we compare a shear-rate dependent fluid (SDF) constitutive model, based on the works by Yasuda et al inagainst a Newtonian model of by: Hemodynamic analysis was performed at various bifurcations.

Patients with stenotic vessels have larger angles 1 and 2 ( ± 11° and 42 ± 20°) and smaller diameters of the external carotid artery (ECA) ( ± mm) compared with control subjects ( ± 13° and 36 ± 16°, ± mm) although there is no significant difference in Cited by: Conclusions.

These data demonstrate that in branching human coronary arteries, a close relation exists between translesional hemodynamics and distal coronary flow velocity. Trandesiumd coronary Dow velocity is a new and easily applicable method for determining the.

Histological images from the longitudinal section of four diseased coronary arteries were used, for the first time, to study the pulsatile blood flow distribution within the lumen of the arteries by means of computational fluid dynamics (CFD).

Results indicate a strong dependence of the hemodynamics on the morphology of atherosclerotic lesion. Distinctive flow patterns appear in different Cited by: 3. MATHEMATICAL PHYSIOLOGY – Hemodynamics in Humans: Physiology and Mathematical models – Jerry J.

Batzel, Mostafa Bachar, Franz Kappel, Viraj Bhalani, Jochen G. Raimann and Peter Kotanko ©Encyclopedia of Life Support Systems (EOLSS) • Mean capillary pressure which is the mean pressure at the level of the capillaries.

F: (a) Boundary plots of the coronary arterial walls and shown in green and blue, respectively. (b) (d) WSS distribution along coronary walls at time 1, 2,and 3,respectively. rate is greater than S 1 [, ]. is assumption is feasible for coronary artery.

e time-dependent Navier-Stokesequationsgoverntheblood owinthecoronaryartery, as =0, + = +. @article{osti_, title = {Reduction of Late In-Stent Stenosis in a Porcine Coronary Artery Model by Cobalt Chromium Stents with a Nanocoat of Polyphosphazene (Polyzene-F)}, author = {Stampfl, Ulrike and Sommer, Christof-Matthias and Thierjung, Heidi and Stampfl, Sibylle and Lopez-Benitez, Ruben and Radeleff, Boris and Berger, Irina and Richter, Goetz M., E-mail: [email protected] Right coronary artery arises from the anterior sinus of Valsalva and courses through the right atrioventricular groove between the right atrium and right ventricle to the inferior part of the septum.

The right coronary artery (RCA) presents a wide morphological expression especially for its length, size, and number of branches, emergence sites. Right coronary artery arises from the anterior sinus of Valsalva and courses through the right atrioventricular groove between the right atrium and right ventricle to the inferior part of the septum.

The right coronary artery (RCA) presents a wide morphological expression especially for its length, size, and number of branches, emergence sites and.

Co-dominant coronary circulation is defined as, when posterior crux of the heart receives twigs from both right and left system making this water shed area with advantage of twin essentially supply inferior and posterior aspect of both left and right ventricle including the posterior aspect of interventricular septum.

Abstract. Arterial stenosis plays an important role in the progressions of thrombosis and stroke. In the present study, a standard axisymmetric tube model of the stenotic artery is introduced and the degree of stenosis η is evaluated by the area ratio of the blockage to the normal vessel.

A normal case and four stenotic cases of, and with a constant Reynolds number of Cited by: 4. (LAD) coronary artery through a 6-French Judkins right catheter. A balloon catheter with a diameter of mm and a length of 8 mm was slid along the press wire to the proximal LAD coronary artery.

Different degrees of luminal obstruction were sim-ulated by inflating the balloon at known pressures. An FFR measurement of less than was used to.

Influence of cardiac hemodynamic parameters on coronary artery opacification with slice computed tomography Abstract The purpose of this study was to evaluate the influence of ejection fraction (EF), stroke volume (SV), heart rate, and cardiac output (CO) on coronary artery opacification with slice computed tomography (CT).

50 healthy volunteers (control group) and 43 patients with carotid abnormalities (CAs) were examined on T MR-scanner using routine MR protocol and quantitative MR angiography (qMRA) for estimate of the arterial blood flow velocity and cross sectional area of the : Yuliya Stankevich, Mariya Rezakova, Bogomyakova Olga, Liubov Shraibman, Andrey Tulupov.

coronary artery, LCX = left circumflex artery. The coronary angiography (CA) and the spiral CT investigation detected a multiple sever right coronary artery (RCA) stenosis (Fig.

1 and Fig 2). The Vascular Model: the coronary artery model simulating the flow field in the RCA (right coronary artery) is illustrated in Figure 4c. The RCA is modelled. patients. It is important to assess the cerebral hemodynamic status in these patients because hemodynamic compromise markedly increases the risk of a subsequent stroke in patients with occlusive cerebral artery disease The cerebral hemodynamic studies in terms of chronic MCA occlusion are much fewer than those of carotid by: Coronary artery disease (CAD), which is characterized by the presence of coronary artery stenosis, is the frequent cause of death worldwide.

The aim of this study was to assess hemodynamic effect due to the presence of non critical coronary stenoses. The computational fluid dynamics (CFD) was used to Cited by: 4.

Int J Anat Res3(3) ISSN Original Article MORPHOMETRIC STUDY OF THE RIGHT CORONARY ARTERY El Sayed S. Atta-Alla*1, Ezzat A. El Sawa 2, Ahmed E.S. Atta-Alla3, Ezdihar A. El Baassiri 4, Khodor Haidar Hassan 5. ABSTRACT. Chronic middle cerebral artery (MCA) occlusion as a cause of hemodynamic stroke has not been a prominent clinical issue in the Western world.

The most common cause of MCA occlusion is embolism, and sudden occlusion of the proximal MCA by an embolus is one of the most frequent causes of major stroke. 1 In addition, emboli, especially those from the heart, frequently undergo lysis, and no Cited by: Although numerous techniques that are based on CT number analysis have been proposed, the assessment of hemodynamically significant coronary artery stenosis remains a great challenge.

The purpose of this study is to validate use of the CT enhancement ratio in the detection of hemodynamically significant coronary artery stenosis in a porcine by: 2.

A Numerical Study of Blood Flow Patterns in Anatomically Realistic and Simplified End-to-Side Anastomoses J. Moore. Moore. “Hemodynamic and histomorphometric measurements in the human right coronary artery,” in: K. Chandran, R.

Vanderby, Jr., Cited by: morphological and blood flow velocity data of patient´s carotid artery cervical segments, surface reconstruction, blood flow simulation and hemodynamic analysis. In this study, ultrasound data from six CCA bifurcations, referred in this study as patients P1 to P6, were analyzed.

Background and Purpose Studies have suggested that the caudal ventral artery is a potential site for continuous arterial blood pressure monitoring in rats. However, the agreement of mean arterial pressure values between the femoral artery and the caudal ventral artery has not been investigated.

This study was performed to identify whether the caudal ventral artery could be safely used for. practical introduction to the hemodynamic analysis of the hemodynamicadvantages, limitations and possible clinical alterations. Principles of the 2D cine PCA The from left to right shows both the magnitude image and velocity images in the x- y- z-axes, respectively.

To better understand the response of the arterial wall to the adjacent blood flow, corresponding hemodynamic and histomorphometric data are obtained at multiple sites in human arteries. The hemodynamic data are obtained by perfusing realistically compliant flow-through casts of vascular segments with physiologically realistic pulsatile flows Author: M.

Friedman. Prevalence of hemodynamically significant stenosis of the carotid artery in an asymptomatic veteran population. Surgery Gynecology and Obstetrics, (1), Prevalence of hemodynamically significant stenosis of the carotid artery in an asymptomatic veteran by: Pattern of coronary artery dominancy by coronary angiography in Iraqi patients & the relationship with coronary artery disease n Ali Fakhir.د.

م Table and figure 1 shows that the right coronary artery was dominant in (76, 4%) patients enrolled in. a CT dataset available as part of Rotterdam coronary artery algorithm evaluation framework [14].

Extraction of the vessel lumen from the three dimensional image data is carried out using an open source image segmentation software, Vascular modelling toolkit (VMTK) [15]. VMTK is a framework which can be used for the analysis, visualisation and.Posterolateral and anterolateral longitudinal B-mode images of the right common carotid artery (CC), the bulb, and the internal (IC) and external (EC) carotids were recorded at end diastole (timed on the basis of the peak of the R wave on the electrocardiogram).

All images were stored on Cited by:   To demonstrate the applicability of the developed methods, we apply the method in the pulmonary artery and aorta of sixteen volunteers 12 males and 4 females, mean age 30 ± 5 years old (Matrix xx54, voxel size xx mm, TR/TE / ms, Flip an VENC cm/s), in which we acquired 3D cine PC-MRI by: 3.

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